Right now, YPN is more vauable to my network (in general) than AdSense. I'm sure the honeymoon will be over soon, but my response is based on YPN clicks only.
In my network I have sites that cator to everyone from children to people in their 60's, and I would say that I get the most clicks, sometimes only by a small margin, from sites targeting 25 to 40 year old American Women.
But like you pointed out, I do nearly just as good targeting 18 to 25 year old North American/United Kingdom men.