I've been a Tucows/OpenSRS reseller for about 5 years now, and I still have a couple hundred domains on their system.
Last month, I finally decided to give WildWestDomains a shot and I'll give you my reasons and observations:
1. Unlike OpenSRS and a lot of other reseller programs, WWD gives you a "retail" looking branded site. The lack of a retail looking interface, meant that all of my activity was in-house accounts only.
2. Unfortunately, registering domains with the retail interface is much slower than using Tucows/OpenSRS. With Tucows, I was able to just fund an account from time to time, and just register domains with only one click and vritually no filling out of forms. Billing, contact info and everything else was automatic. WWD's interface is much slower and you need to pay for each registration as you order it rather than from a funded account... which slows me down.
3. Thus far, in spite of the fancy virtual storefront, I've still never sold a domain to the public... so I'm still just using it for in-house accounts. Not a problem mind you, but just an observation that people still look for a brand they know. BUT... It's nice to know that if I spend some time/money I have at least the POTENTIAL to sell retail.
4. WWD's reporting is more primative, so managing my domain list is a bit more difficult. Tucows/OpenSRS has lots of reports and exports to CSV, so I can keep track of them in my own databases.
5. The prices are pretty good. A savings of about $3 per year for the doman, and free DNS, email forwarding, etc... So I'm saving far more than the cost they charge to create the reseller account.